The entire route forms part of Asian Highway 3.

The Jiangxi portion of the expressway passes through the cities of Shangrao, Nanchang, Yichun, and Pingxiang.

The Hunan section of the expressway passes through the cities of Zhuzhou, Shaoyang, and Huaihua.

The Kaima Expressway connects Kaili City to Majiang County.

In Yunnan Province, the expressway passes through the city of Qujing before terminating in Kunming.