Humacao (Spanish pronunciation: [umaˈkao]) is a city and municipality in Puerto Rico located in the eastern coast of the island, north of Yabucoa; south of Naguabo; east of Las Piedras; and west of Vieques Passage.

It is believed that the Taíno chief Jumacao was the first "cacique" to learn to read and write in Spanish, since he wrote a letter to the King of Spain Charles I complaining about how the Governor of the island wasn't complying with their peace agreement.

[7] Still, some settlers remained and by 1776, historian Fray Íñigo Abbad y Lasierra visited the area and wrote about the population there.

In 1899, after the United States invasion of the island as a result of the Spanish–American War, the municipality of Las Piedras was annexed to Humacao.

[7] Puerto Rico was ceded by Spain in the aftermath of the Spanish–American War under the terms of the Treaty of Paris of 1898 and became a territory of the United States.

In 1899, the United States Department of War conducted a census of Puerto Rico finding that the population of Humacao was 14,313.

A basketball star in his early years, Trujillo has pushed for the development of infrastructure facilities for sports and the fine arts in the city.

Its first bishop is Monsignor Eusebio 'Chebito' Ramos Morales, a maunabeño who was rector of the Humacao's main parish in the 1990s.

In 2019, Luis Raul Sanchez became interim mayor of Humacao after Marcelo Trujillo Panisse died in September 2019.

[12] Humacao was working on flood mitigation plans and shared that its barrios located on the coast; Antón Ruíz, Punta Santiago, Río Abajo, Buena Vista and Candelero Abajo barrios, are extremely vulnerable to flooding and destruction.

Of the 742 places that were on the list in 2014, the following barrios, communities, sectors, or neighborhoods were in Humacao: Antón Ruiz, Obrera neighborhood, Cotto Mabú-Fermina, Buena Vista, Parcelas Aniseto Cruz in Candelero Abajo, Parcelas Martínez in Candelero Abajo, Cataño, Punta Santiago, Verde Mar, and Cangrejos.

[34] Due to its location on the coast and relative short distance from the capital, Humacao is a frequent stop for tourists.

The resort contains tennis courts, two world-class golf courses, beach access, several restaurants and a riding center.

The Fiestas Patronales Inmaculada Concepcion de Maria is a religious and cultural celebration that generally features parades, games, artisans, amusement rides, regional food, and live entertainment.

Most years it has been held at one of the highest elevations within the sector with views to Humacao, Las Piedras, Naguabo, Vieques and Yabucoa.

The current mayor of Humacao is former Senator Rosamar Trujillo Plumey, of the Popular Democratic Party (PPD).

In 2024, Wanda Soto Tolentino and Luis Daniel Colón La Santa were elected as District Senators.

[46] It consists of three horizontal stripes: gold that stands for Chief Jumacao's crown, red that symbolizes the coat of arms and the green that represents the arrows used by the Taínos.

Puerto Rico Highway 3, the main highway bordering the east coastline of Puerto Rico from San Juan, passes through Humacao and has its only alt route in the town, known locally as the Bulevar del Rio (River Boulevard) where it has access to the main judiciary center of the city, as well as a future theatre that is being built, the Centro de Bellas Artes de Humacao (Humacao Fine Arts Center).

It also manages an astronomical observatory where many tourists and locals come visit and view the stars and planets and the Museo Casa Roig where arts expositions and cultural events are celebrated.