[4] The community lies on Missouri Route A in the southwest corner of the county.

[5] As of the census[7] of 2010, there were 336 people, 122 households, and 89 families residing in the city.

There were 141 housing units at an average density of 213.6 per square mile (82.5/km2).

23.8% of all households were made up of individuals, and 6.5% had someone living alone who was 65 years of age or older.

There were 141 housing units at an average density of 206.8 per square mile (79.8/km2).

21.3% of all households were made up of individuals, and 9.0% had someone living alone who was 65 years of age or older.

The mascot for Hume is the Hornets, with red and white as school colors.

Native Americans are thought to have buried their dead in a mound structure approximately one mile north of Hume, although there is no evidence to support this claim.

The Bleeding Kansas affair and the upcoming Civil War brought John Brown to this area with an attack on the Lawrence farm, five miles south of Hume, in which slaves were freed.

11 was signed by Gen. Thomas Ewing and led to a burning of settlements in the Hume area.

[10] Noah Little had to redraw Taylor's Plat and designed the town of Hume.

The bank scandal in 2008 was completely caused by fiscal mismanagement and embezzlement.

In 2009, previous Hume Bank president, Jeffrey W. Thompson, 40, of Hume, Mo., pleaded guilty before U.S. Magistrate Judge Sarah W. Hays to the charges of making false statements to the FDIC as part of a bank fraud scheme that caused such significant losses that the bank was pushed into insolvency.

In 2011 Jeff Thompson was sentenced to six years, six months in Federal prison without the possibility of parole.