In Simmern it connected with the now partially closed Hunsrückquerbahn (Trans-Hunsrück Railway) between Langenlonsheim and Hermeskeil.

On the 15 kilometre-long Boppard–Emmelshausen section there are regular local services operated by Rhenus Veniro as route RB 37.

These original Hunsrückbahn is now called the Hunsrückquerbahn (literally meaning the “Trans-Hunsrück Railway”) to distinguish them (especially since the development of Hahn Airport).

Not only the steep route between Boppard and Buchholz, but also the line through the front ridge of the Hunsrück required a high standard of technology and a substantial workforce.

The most serious accident occurred on 4 January 1907 in the drilling of the tunnel between Leiningen and Lamscheid when a worker was crushed by a landslide.

In the years since 1998, the section has been gradually dismantled and the Schinderhannes cycle path was built on the Emmelshausen–Simmern route, which is very popular with cyclists, skaters and walkers.

The DB Netz AG invested €9.3 million on the line to completely replace the old tracks and sleepers.

Rhenus Veniro was contracted to take over passenger operations on the Hunsrück railway at the timetable change in December 2009.

The Public Transport Association of Rhineland-Palatinate North (Zweckverband SchienenPersonenNahVerkehr Rheinland-Pfalz Nord) in Koblenz had awarded the company the contract for its operation in February 2008.

Rhenus Veniro was contracted to operate three Stadler Regio-Shuttle RS1 diesel multiple units that were modified for the steep grades of this route.

On the last day before the Easter school holidays on the 15 April 2011, Zweckverband SPNV-Nord terminated the operations of DB Regio on the line.

On 29 April 2011, the Federal Railway Authority issued a limited operating license to Rhenus Veniro for the three RS1 DMUs (650350–650352), valid to 31 December 2011, allowing them to be used.