Huron and Eastern Railway (reporting mark HESR) is a short line railroad operating 394 miles (634 km)[1][2] of track in The Thumb and Flint/Tri-Cities area of the lower peninsula of Michigan.

This track served areas in Huron and Sanilac Counties, roughly between Bad Axe and Croswell, with a few spurs to outlying small towns.

On January 22, 1991, HESR again added more track to its system, acquiring a cluster of former Penn Central lines from the Tuscola and Saginaw Bay Railway.

Huron and Eastern's locomotive power is a mix of former Central Michigan, Saginaw Valley, and original HESR rolling stock.

[1] The railroad's traffic comes largely from agricultural products, as well as industrial goods, such as cement, fly ash, and chemicals.