[3] In the primary, he beat running mates Shamsi Vuai Nahodha, former Chief Minister of Zanzibar, and Dr. Khalid Mohamed, who served as the Permanent Secretary for the Second Vice President.

The CCM’s 164 National Executive Committee members voted in July 2020, with 78.65% in favor of Mwinyi’s nomination to lead the party in the General Election.

[9] Under his administration, 289 cases have been prosecuted by the Zanzibar Anti-corruption and Economic Crimes Authority, or ZAECA, leading to hundreds of millions of dollars in government funds saved from being embezzled or laundered.

[10] This includes the suspension, but not removal, of Zanzibar Social Security Fund director Sabra Issa Machano, and an official for the Tanzania Revenue Authority.

[12] In January 2022, the government allocated 149 billion Tanzanian shillings (equivalent to 68 million US Dollars) to develop the archipelago’s blue economy, buying various fishing equipment.

[10] In addition, he established Zanzibar's first Ministry of Blue Economy and Fisheries, which was praised by experts for aiming to address the adverse effects of climate change on the country's seaweed industry.

[16] In his first year in office, he eliminated the possibility for bail for all sexual offenses, and said that "We will place greater emphasis on eliminating various forms of violence against women, especially those in rural areas, and also improve social services, reduce maternal mortality, as well take water closer to women" [14][17] Mwinyi has had a positive relationship with China since he was the Minister of Defense and National Service for Tanzania.