Hussein Mahmoud Hassan el-Shafei (Arabic: حسين محمود حسن الشافعي; 8 February 1918 – 18 November 2005) was an Egyptian military officer who was a member of the Free Officers Movement and served as vice president under two Egyptian presidents, Gamal Abdel Nasser and Anwar Sadat.

He was one of the nine men who had constituted themselves as the committee of the Free Officers movement and led the country's cavalry corps during the uprising, and was one of only three last-surviving members of the Revolutionary Command Council at the time of his death.

He served as vice-president under Gamal Abdel Nasser in 1961.During his tenure as minister of social affairs, el-Shafei introduced social insurance reforms considered radical at the time, including pensions to widows.

Some Egyptian celebrities took part in the "mercy trains" which delivered the goods, including actress Faten Hamama.

Anwar Sadat appointed el-Shafei as vice-president of Egypt's new government in 1971 and he was succeeded by Hosni Mubarak in April 1975.