Huvishka's territory encompassed Balkh in Bactria to Mathura in India, locations where it is known that he minted his coinage.

Gold coins and amulets in his effigy were found as far as Pataliputra and Bodh Gaya, including one such amulet as an offering under the Enlightenment Throne of the Buddha in Bodh Gaya, suggesting with other finds of Kushan coins in the area that Kushan rule may have extended this far east.

The reign of Huvishka corresponds with the first known epigraphic evidence of the Buddha Amitabha, on the bottom part of a 2nd-century statue which has been found in Govindo-Nagar, and now at the Mathura Museum.

The statue is dated to "the 28th year of the reign of Huvishka", and dedicated to "Amitabha Buddha" by a family of merchants.

A Sanskrit manuscript fragment in the Schøyen Collection describes Huvishka as one who has "set forth in the Mahāyāna."

[11] Huvishka also incorporates in his coins for the first and only time in Kushan coinage the Hellenistic-Egyptian Serapis (under the name ϹΑΡΑΠΟ, "Sarapo").

[23][24] In a departure from his predecessor Kanishka, Huvishka also added Oesho ("ΟΗϷΟ", Shiva) on some of his coinage.

The devaluation led to a massive production of imitations, and an economic demand for the older, pre-devaluation coins in the Gangetic valley.