Hyainailourinae ("hyena-cats") is an extinct subfamily of hyainailourid hyaenodonts that lived in Africa, Asia, North America and Europe from the middle Eocene to middle Miocene.

[5][6][7][8] They appeared in Africa about 47.8 Ma ago and soon after spread as far as East Asia.

[9] Cladogram of Hyainailourinae from Morales and Pickford, 2017:[11] Mlanyama sugu Buhakia spp.

Dissopsalis carnifex Leakitherium hiwegi Pterodon africanus Hyainailouros spp.

Sectisodon markgrafti Sectisodon occultus Exiguodon pilgrimi Falcatodon schlosseri Isohyaenodon zadoki Metapterodon spp.