Saburō Hyakutake (Japanese: 百武三郎) (June 3, 1872 – October 30, 1963) was an Imperial Japanese Navy admiral.

Hyakutake was born in Saga Prefecture.

His younger brothers Gengo and Harukichi also became high ranking military officers.

Hyakutake was a graduate of the Imperial Japanese Naval Academy and the Naval War College.

He was Grand Chamberlain of Japan (1936–1944).