It is a stop on the Hope Valley line, hosting services between Manchester Piccadilly and Rose Hill Marple.

From 1862, the branch was extended to New Mills to meet the Midland Railway's extension of its line from Millers Dale.

The substantial station buildings were demolished in 1980, with a new booking office at street level commissioned in their place.

In July 2020, Northern informed local residents that services between Manchester and Rose Hill Marple would not operate between early September and mid-December 2020;[1] this was due to the effects of the COVID-19 pandemic on their workforce.

Hyde Central is served by hourly trains in each direction on Mondays to Saturdays, with some additional services during the day between Manchester Piccadilly and Rose Hill Marple, via Guide Bridge.