Hyde Park moved to its present site at 6220 South Stony Island Avenue in July 1914.

[9] In January 1966, The Chicago board of education was charged with violation federal and state laws when they approved a plan to modernize Hyde Park (due to its growing population of African–Americans) and build a new high school that would serve Hyde Park's current white student body also attracting other white students located next to the school.

[12][13] Hyde Park began to offer International Baccalaureate classes to its students during the 2000–2001 school year.

Under this program, Hyde Park was forced to accept more than 300 more area–students than any other high school in the city during a two–year period.

On February 15, 2013, President Barack Obama delivered a televised speech in the school's gymnasium addressing the issue of gun violence in Chicago.

[15][16][17] Hyde Park competes in the Chicago Public League (CPL) and is a member of the Illinois High School Association (IHSA).