[1][5] The threats to this species are poorly known, but it is probably impacted by habitat loss caused by agriculture, livestock, wood extraction, and human settlements.

[8] Habitat loss, primarily driven by the conversion of land for agriculture and livestock, poses a significant threat to the São Tomé Giant Reed Frog.

Additionally, the species faces challenges from habitat reduction due to activities such as wood extraction and the expansion of human settlements.

[1] A survey conducted for the presence of the amphibian chytrid fungus (Bd) revealed infections dating back to 2001.

However, the highly virulent strain of the pathogen (Bd-GPL) present on São Tomé Island raises concerns about its potential threat to the species.