The song was a number one hit on Billboard's Hot R&B Sides chart, and also peaked at No.

[1] Following the smash success of Cooke's debut single "You Send Me" on Keen Records, Speciality owner Art Rupe quickly rushed out "I'll Come Running Back to You" as a single.

[1] Rupe instructed arranger René Hall to duplicate the sound of "You Send Me", which included overdubbing similar instrumentation and background singers.

[2] Speciality purchased a three-fifths-of-a-page ad in the November 25 issue of Billboard to promote the single.

[3] Credits adapted from the liner notes to the 2003 compilation Portrait of a Legend: 1951–1964.