ID-4708

ID-4708 is a butyrophenone neuroleptic agent.

It has the same structure as for trifluperidol but differs by the incorporation of an aniline amino group into the butyrophenone sidechain.

Whereas trifluperidol is a Belgian drug developed at Janssen Pharmaceuticals, ID-4708 was developed by a Japanese company called Sumitomo Chemical in the 1970’s.

ID-4708 when given at low doses reduced ambulation, while at higher doses defecation was inhibited.

[1] The chemical synthesis of ID-4708 was reported:[2][3]

ID-4708 synthesis
ID-4708 synthesis