"I Can't Lose" is a song by English DJ and record producer Mark Ronson with featured vocals by Keyone Starr.

The song is a promotional single from Ronson's fourth studio album Uptown Special, released on 13 January 2015.

This trawling process led to Ronson and Bhaskar sifting through "a few hundred amazing singers" in assorted churches, nightclubs, bars and community centres.

[4] However they "had a very specific vocalist in mind", who turned out to be Keyone as both of them realised as she started singing[4] in Mississippi State University.

It features both Ronson and Starr performing in an underground Chinatown club along with assorted musicians.