It is the end of the summer and Elena (Nina Dobrev) and Caroline (Candice Accola) need to get ready for college.
No one knows yet that Bonnie (Kat Graham) is dead, except for Jeremy, who sees her and talks to her and also answers everyone's mails and texts that are sent to her.
At the college party, Megan is killed by a vampire, something that makes Elena and Caroline concerned about their secret and that it may bust open.
Back at the Salvatore house, Katherine makes her unwelcoming appearance asking for Damon's help and protection since now that she is human she is vulnerable and she is scared.
Silas makes his appearance at the town square restaurant, where he meets Sheriff Forbes (Marguerite MacIntyre).
At the end of the episode, Nadia and her partner cast a mysterious spell on Matt who loses his senses.
In the meantime, Stefan is still locked in the safe underwater and is hallucinating scenes where he talks to Damon and later to Elena, while he is fighting the urge to turn off his humanity.
David Griffin of Screen Rant said that the episode is "another stellar season premiere that doesn’t disappoint" and stated that "The Vampire Diaries has a cruel way of reminding viewers that no character is safe in this world.