[5] "I Know You Want Me (Calle Ocho)" is an uptempo syncopated hip hop groove with clear vocals on the chorus and a pop hook, within a tribal house-oriented beat.

The song is set in common time with a moderate tempo of 128 beats per minute and is written in the key of D minor.

At the core is an acoustic guitar and a sizzling rhythm, with hot horns in the form of a sample that just keeps on giving: Chicago's "Street Player," which appeared in the '90s techno hit "The Bomb" by the Bucketheads.

Mainstream radio missed out on Pitbull's previous single "Krazy," featuring Lil Jon, but "Calle Ocho" is already on the top half of the Billboard Hot 100, and the temperature on the street and in the clubs is rising".

He said it was meant to be sexy given how Pitbull performed the verses, but is fun and 'more gigglesome than wrigglesome', and wondered if its effect would vary between listeners of different genders: "I don't know if it has a different effect on The Ladies, but I'm basically fine with a pumped up dance version of a very familiar piece of music, with a funny man on the top shouting about how aroused he is and occasionally counting on his fingers.

On November 11, 2009, the single was certified double platinum by the Recording Industry Association of America (RIAA) for sales of over two million digital copies.

It features Pitbull, Nayer (wearing a peaked cap), and models Sagia Castañeda, Maria Milian, and Angelica Casañas.