Between 1842 and 1848, Ion Ionescu de la Brad set up the first classes for agricultural education in Romania, within the Academia Mihăileană.

[2] In 1933, the department was reorganized as the Faculty of Agricultural Sciences of the University of Iași, and based in Chișinău.

In 1937, the faculty became administratively part of the newly established Gheorghe Asachi Polytechnic School, keeping its location in Chișinău.

Following the occupation of Bessarabia by the Soviet Union, the faculty from Chișinău became independent as the Chișinău Agricultural Institute (nowadays State Agrarian University of Moldova), while in Iași the Faculty of Agronomy was re-established within the Polytechnic School.

In 1990, the Agronomic Institute was renamed as the Ion Ionescu de la Brad University of Agricultural Sciences and Veterinary Medicine.