Nagle began his career with home province Munster, before stints abroad with English sides Newcastle Falcons and London Irish.
[5] It was announced in February 2014 that Nagle would be joining Aviva Premiership side Newcastle Falcons on a short-term loan.
[6] In February 2016, Nagle made his return to professional rugby when he signed with Aviva Premiership side London Irish for the remainder of the 2015–16 season.
[8] Nagle joined Ulster on loan in November 2018, in a deal that saw him remain with the province until the end of the 2018–19 season.
[16] Nagle started Emerging Ireland's second game, a 19-8 defeat at the hands of South Africa President's XV on 11 June 2013.