Iciss Tillis (born December 6, 1981) is an American professional women's basketball player.

Tillis played for Cascia Prep School in Tulsa, Oklahoma, where she was named a WBCA All-American.

James Tillis fought for the Heavyweight championship once and was the first professional boxer to fight Mike Tyson to a decision.

Tillis has played in the WNBA with the Detroit Shock, New York Liberty, and Los Angeles Sparks, appearing in 66 games.

A scandal erupted in France, where Tarbes Gespe Bigorre attempted to sign Tillis to replace injured star Isabelle Yacoubou despite being over the eligible limit of non-European players imposed by the Ligue Féminine de Basketball.