Ignatius III David was the Patriarch of Antioch and head of the Syriac Orthodox Church from 1222 until 1252.
[4] The former maphrian, Ignatius Sleeba III of Edessa, after having retired and became a physician, is known to have treated David, who suffered from gout.
During David's tenure as patriarch, a dispute arose between the Syriac Orthodox Church and Pope Cyril III of Alexandria of the Coptic Orthodox Church, who, in 1237, had taken advantage of the military strength of the Ayyubid Sultanate to appoint a Coptic bishop of Jerusalem.
Upon hearing of the appointment of a new abuna, the Dominicans incited the Templar and Hospitaller knights to meet with David and demand an explanation.
[5] In the closing years of his tenure as patriarch, David entered a quarrel with the metropolitan bishop Dionysius Angur of Melitene.