Ignazio Camillo Guglielmo Maria Pietro Persico (30 January 1823 – 7 December 1895) was an Italian cardinal of the Roman Catholic Church.

During the Indian Rebellion of 1857 against British occupation forces, Persico was in danger several times, causing his health to deteriorate.

[1] On 14 March 1887, Leo XIII promoted Persico to the Roman Curia and appointed him as titular archbishop of Tamiatha.

[1] Persico quickly realized that he needed to consider the history of Ireland in addition to current politics and delayed his report to analyze it.

On 23 April 1888, before Persico could complete his report, the Congregation of the Holy Office declared its opposition to the Plan of Campaign and condemned the use of boycotting by Irish activists.

According to author Edward Purcell, this ruling was a surprise and disappointment for Persico:"The promulgation of the Papal Rescript, condemning boycotting and the Plan of Campaign as grave offences against the moral law, took Mgr.

Persico as much by surprise as it did Cardinal Manning; for both he and the Papal Delegate confidently expected that, in accordance with their joint suggestions, the condemnation of the immoral methods of the League would have been pronounced not directly by the Holy See, but by the Irish Episcopate.

He later commented, "I had no idea that anything had been done about Irish affairs, much less thought that some questions had been referred to the Holy Office, and the first knowledge I had of the decree was on the morning of the 28th April, when I received the bare circular sent me by Propaganda.

[10] Persico died in Rome on 7 December 1895 and was buried at the Church of Propaganda Fide, Campo Verano cemetery.