Isaiah "Ike" Reese (born October 16, 1973) is an American sports radio host and former professional football player.

Reese played college football for the Michigan State Spartans and was selected by the Philadelphia Eagles in fifth round of the 1998 NFL draft.

[2] After redshirting his freshman year, Reese played for the Michigan State Spartans football team from the 1994 to 1997 seasons as a starter.

In 2008, Reese began hosting Ike at Night evenings on 610 WIP Sportsradio in Philadelphia.

Following Marks’ departure at the end of 2023, Ike was partnered with Fritz and Spike Eskin as co-hosts of the 94.1 WIP Afternoon Show.