Ilhéu de Santa Maria (once known as Quail Island) is a small uninhabited islet of the Sotavento archipelago in Cape Verde located off the shore of the island Santiago.

Like all Cape Verdean islands, the islet is of volcanic origin.

[1]: 133  The buildings have been used for quarantine as well, but this was moved to the new Lazareto on Ponta Temerosa in the 1870s.

[1]: 134 In 2015, the Cape Verdean government and the Chinese-based Legend Development Company agreed on construction of a hotel resort and casino on the islet.

[2] As of May 2018, the bridge from the islet to the mainland has been completed, and construction of the hotel and casino are due to start in August 2018.