ʽImad al-Din Maẖmud ibn Masʽud Shirazi (عمادالدین محمود بن مسعود شیرازی) was a mid-16th-century Persian physician from Shiraz, Iran.
‘Imad al-Din Mahmud Shirazi resorted to opium during that night, and, although he recovered from the immediate effects of the cold, he had a tremor for the rest of his life.
Reflecting his own experience, ‘Imad al-Din Mahmud Shirazi wrote a treatise in Persian on the medical and addictive properties of opium and its use in compound remedies.
The National Library of Medicine has a copy of this treatise that was made in Kerman in 1591, possibly during the author's lifetime or shortly thereafter.
Another copy of this 16th-century Persian manuscript scribed between 1737 and 1744 is extant in the Library of Ibn Sina Academy of Medieval Medicine and Sciences.