The Imāmzādeh Hamzah (Persian: امامزاده سيد حمزه) is a Twelver Shī‘ah Imamzadeh and mosque complex in Tabrīz, Iran.

The mosque contains the grave of Hamzah, son of the Twelver Imām, Mūsā al-Kāzim.

The Imāmzādeh Hamzah mosque is located in the Sheshghelan suburb of Tabrīz, next to Maqbaratoshoara and the Museum of Ostad Bohtouni.

Sayyid Abi al-Qasim Hamzah was a son of Imam Musa ibn Ja'far al-Kazim, who was credited for the genealogy of the Saffavids.

The style of decoration of the Hamzah Mosque is further enhanced and has therefore enjoyed sustained patronage.