[6] Founded by the Sisters, Servants of the Immaculate Heart of Mary, Immaculata is part of the greater IHM community, which includes the neighboring House of Studies and an academy for girls (now split into two campuses, Lower School and High School).

The current location of Immaculata University is in the Great Valley region of Chester County, Pennsylvania, near the Philadelphia Main Line community of Malvern, purchased by the sisters in 1906.

In June 2002, Immaculata College received confirmation of university status from the Pennsylvania Department of Education.

Varsity Teams: Conference: Colonial States Athletic Conference (CSAC) through 2017–18; Atlantic East Conference thereafter[9] Affiliation: NCAA Division III Nickname: Mighty Macs Colors: Blue and White[10] Draper Walsh Stadium (Sprint turf surface) for field hockey, lacrosse, and soccer – 1,000 capacity IU Softball Field (grass) IU Baseball Stadium (grass) – 600 capacity There is a Student-Athlete Advisory Committee (SAAC) which encourages athletics.

[12] On January 26, 1975, Immaculata played in the first nationally televised women's intercollegiate basketball game.

[20] Players Theresa Grentz and Marianne Stanley were inducted into the Naismith Hall in 2022 for their subsequent accomplishments as college coaches.

The three-storied Gabriele Library contains computers and study rooms and houses the writing center and archives along with a coffee shop on the first level, which is called the ImmacuLatte.

The Lillian P. Lettiere Center houses financial aid and admissions and also the Esports arena.

Loyola Hall is the university's second main classroom building and contains administrative offices—College of Graduate Studies, nursing and allied health sciences, amphitheaters, art, education, mathematics, psychology, science departments, computer centers, curriculum library, laboratories, and math center.

Villa Maria Hall, with its Italian Renaissance architecture, is a beautiful building capped by a dome.

With the vision of the IHM Sisters, Villa Maria Hall was placed between Harrisburg and Philadelphia in order to have a convenient location to build a college for women.