Major historical contributions including publication by Donald Metcalf of the strategy for identifying colony-stimulating factors (CSFs)[3] and the development of the clonal selection theory by Frank Macfarlane Burnet, in a series of more than 90 publications in the 1970s.

The journal's editor-in-chief is Adrian Liston, with Jonathan Coquet, James Harris, Kate Lawlor, Michelle Linterman, and Fabio Luciani serving as deputy editors.

[4] ICB has a sister journal, Clinical and Translational Immunology,[5] which was founded in 2012 in response to a growing need for publishing clinically-orientated research papers in the field of immunology.

Each year, the ASI Annual Scientific Meeting hosts a dedicated workshop session to recognise the authors of top papers published in CTI and ICB.

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