The magazine is focused on celebrity news, fashion, beauty, relationships and lifestyle, and is geared towards a younger readership, billing itself as "fast and fun", along with making claims about their lower cover price on their front cover to encourage buyers to purchase their magazine rather than the other titles on a supermarket checkout rack.

Whereas In Touch is focused more on celebrity gossip, Life & Style bills itself on giving readers lifestyle tips on how to incorporate celebrity beauty and fashion into their lives.

On September 18, 2006, after the death of Daniel Wayne Smith, son of Anna Nicole Smith, Getty Images sold the last photos taken of Daniel alive at his mother's bedside to In Touch Weekly and Entertainment Tonight for a reported $650,000.

Although the magazine was criticized for releasing the report, the Springdale, Arkansas, city attorney and several legal experts said that since Josh was 18 at the time of the investigation and all minors' names were redacted, the release was permitted under Arkansas' Freedom of Information Act.

[4][5][6][7][8][9][10] In Touch Weekly and its successive parent companies have faced lawsuits from people including Duggar, Richard Simmons, Blake Shelton, David Beckham, Tom Cruise and Judy Sheindlin alleging causes of action including defamation and invasion of privacy.