The series is set in Los Angeles, and depicts the lives of the Fisher family, who run a funeral home, along with their friends and lovers.
For the episode, Peter Krause received a nomination for Outstanding Lead Actor in a Drama Series at the 54th Primetime Emmy Awards.
This is shown to be part of a movie premiere, with the actress Rebecca Milford (Alexandra Holden) delighted with reactions.
Rebecca's boyfriend, Brody Farrell (Shawn Hatosy), visits Fisher & Sons to arrange her funeral, as he knows Federico (Freddy Rodriguez) through his sister-in-law.
As she still recovers from the car crash, Brenda (Rachel Griffiths) has been feeling unsatisfied while having sex with Nate (Peter Krause), who has not told his family about his medical diagnosis.
Feeling discontent with his love life, David visits Keith (Mathew St. Patrick) at his church, finding him with Eddie.
Ruth (Frances Conroy) starts reading a book to understand gay culture, and invites Nikolai (Ed O'Ross) to dine with her family, leading to an awkward meeting when she talks about her sexual life.
The dim-witted Brody's ridiculous eulogy song (and Claire's reaction to it) is hilarious, and Nate's bizarre hallucination in which Life and Death get way too intimate is simultaneously creepy and funny.
Nate's trip leads to one of the odder fantasy moments of the series, as he and his father watch Life and Death personified having sex in front of them.
“In the Game” has plenty of nice allusions to the series premiere, but it also feels like Six Feet Under trying to find its footing after the break.
"[10] Peter Krause submitted the episode to support his nomination for Outstanding Lead Actor in a Drama Series at the 54th Primetime Emmy Awards.