It is constituted as one of the main access roads to the historic centre of Lima and extends from north to south along 12 blocks.

[1] Although during the government of General Juan Velasco Alvarado the name was changed to the more autochthonous Inca Garcilaso de la Vega, in honor of the first mestizo writer in Peru, the name Wilson continues to be used by locals to this day.

[3][4] In its twelve-block route, the main highlights are its blocks 11, 12 and 13, which constitute the largest cluster of computer items in Lima.

The area is the location of many well-known commercial galleries where software and hardware products are sold.

[5] The avenue's intersection with the Avenida España is the location of the former U.S. Embassy,[6][7] today the Clínica Internacional,[8] and of the Casa Matusita, a house known for the popular belief of being of the paranormal type.