Indian cricket team in South Africa in 2010–11

South Africa's David Wiese was ruled out of the T20I series with a fractured hand and was replaced by Albie Morkel.

[4] Rilee Rossouw was ruled out of the ODI series following a stress fracture to his foot and was replaced by Khaya Zondo.

[6] Vernon Philander was ruled out of the last three Test matches after suffering an ankle injury and was replaced by Kyle Abbott.

[7] Marchant de Lange was added to South Africa's Test squad as cover for Dale Steyn.

[9] Indian batsman Sachin Tendulkar suffered a hamstring injury during the match and was forced to fly home afterward.