The Indigenous Peoples Council on Biocolonialism (IPCB) is a non-profit organization based in Nixon, Nevada for the purpose of political activism against the emergent field of population genetics for human migration research.

The term "biocolonialism" is a neologism —a portmanteau of "bio-" and "colonialism" —used by the IPCB to pejoratively characterize population genetics research as part of invasive and destructive assimilation against indigenous peoples.

"[1] In particular, the IPCB's protests were based on a rejection of participating in scientific research that would negate or otherwise contradict traditional Native American accounts and narratives about their ancestral origins, and lend support to other alternate views.

[2] The IPCB was founded in 1999 by the current Executive Director Debra Harry, following her growing concerns over a perceived impact of genetic colonialism on the lives of indigenous peoples.

[3] The organization objects to genetic variation research on isolated populations, as well as its prospective commercial exploration; claiming it as a global threat, not only to the self-determination of all indigenous peoples, but also to the non-indigenous world and to the earth itself.