[4] Some of the Indooroopilly State High School Buildings are listed on the Queensland Heritage Register.

Some of the facilities at the school include:[6] Like all other state high schools in Queensland, ISHS adheres to Australian curriculum standards set by the Australian Curriculum, Assessment and Reporting Authority (ACARA).

Senior high school students may graduate with a Queensland Certificate of Education or an International Baccalaureate Diploma.

One significant festival that is held every year is United Nations Day, where ISHS encourages its student body to celebrate their cultural or ethnic background, be it through the wearing of traditional national clothing or on stage performances.

The Queensland Department of Education had initially said they expected the school would re-open after the deep clean was performed,[11] however this turned out to not be the case.