At a run-down, understaffed hospital, Dr. Akiba refuses to admit a patient with a strange black rash and is alerted to a severe crisis in Room 3, where a burn victim dies, having been given the wrong drug.

The head nurse then discovers that the patient Akiba previously refused to admit has been left in the hallway and informs him.

However, when Akiba goes to check, he discovers that Doctor Akai has taken the patient and decides to study his symptoms; though he is still alive, his body mass is liquefying into green goo.

The head nurse awakens and begins acting strangely while she bleeds green goo from her ears and eyes.

Akiba panics and turns to find the mean nurse, now infected and covered in green goo, smiling and hanging upside down from the ceiling.

[1][2][3] The series was a list of free-standing horror films directed by Masayuki Ochiai, Norio Tsuruta, Takashi Shimizu, Kiyoshi Kurosawa, Hideo Nakata and Hiroshi Takahashi.

[1] The Japan Times stated that Infection will "look familiar to J Horror fans" and resembled an episodes of The X-Files without Scully and Mulder.

His hospital breathes with a menace, madness and despair so pervasive that only a huge, obliterating explosion could bring escape -- in this life, at least.

"[2] David Kalat (Video Watchdog) referred to the film as "a claustrophobic chamber piece" and "an overwhelming sensory experience that employs every cinematic trick in Ochiai's repertoire to establish a tone of intense dread.

"[9] Sight & Sound gave the film a mixed review, opining that "after a fairly engrossing trawl through horror conventions, the film takes a reckless plunge into oneiric ambiguity that fails to provide satisfying closure"[10] Sean Plummer writing in Rue Morgue stated that Infection "gets a bit messy towards the end" as "a major plot twist makes suspension of disbelief difficult" concluding that the film's "take on how a virus is transmitted is pretty original.