[1] ISI actively participated in the information revolution, and it played a leading role in developing and managing the early Internet and its predecessor ARPAnet.
[2][3][4] The Institute conducts basic and applied research supported by more than 20 U.S. government agencies involved in defense, science, health, homeland security, energy and other areas.
[16][17] Researchers also work in scientific data management, wireless technologies, biomimetics and electrical smart grid, in which ISI is advising the Los Angeles Department of Water and Power on a major demonstration project.
[18] Another current initiative involves big data brain imaging jointly with the Keck School of Medicine of USC.
ISI also has partnered with businesses including IBM, Samsung Electronics, Raytheon, GlobalFoundries, Northrop Grumman and Carl Zeiss AG, and currently is working with Micron Technology, Inc., Altera Corporation and Fujitsu Ltd. ISI also operates MOSIS, a multi-project electronic circuit wafer service that has prototyped more than 60,000 chips since 1981.
The Institute also has given rise to several startup and spinoff companies in grid software, geospatial information fusion, machine translation, data integration and other technologies.
He approached the University of California, Los Angeles about creating an off-campus technology institute, but was told that a decision would take 15 months.
Steve Crocker originated the Request for Comments (RFC) series, the written record of the network's technical structure and operation that both documented and shaped the emerging Internet.
[35][36] In 2012, ISI's Kevin Knight spearheaded a successful drive to crack the Copiale cipher, a lengthy encrypted manuscript that had remained unreadable for 250 years.