Lukšaitė was born on 2 February 1940 in Kaunas to the family of banker Kazimieras Lukša [lt] and cultural historian Meilė Lukšienė.
[1] She graduated in 1962 and worked as a teacher in Trakų Vokė until 1964 when she became an aspirant (doctoral student) at the Lithuanian Institute of History.
[5] The monograph sold out quickly[1] and Lukšaitė received the Lithuanian Science Award [lt] for the book.
[3] She prepared several publications of historical sources, including an anthology of texts on the education in Lithuania in the 13th to 16th centuries (with others; 1994), selected works of Andreas Volanus (with Marcelinas Ročka; 1996), Deliciae Prussicae by Matthäus Prätorius (with others; 4 volumes in 1999–2011), and documents on the visitation of Lutheran churches in Klaipėda in 1676–1685 (2009).
[3] Lukšaitė served on the editorial board of academic journals Lietuvos istorijos metraštis, Knygotyra,[5] and book series Senoji lietuvių literatūra.