Several of its principals were involved in the 100 Year Starship winning team originated by NASA and DARPA.

[2] The US activities of i4is are coordinated by the Institute for Interstellar Studies, a not-for-profit registered in Tennessee, USA.

[5][6][7][8][9] The design of the team from the University of California, Santa Barbara, has subsequently been selected as the baseline system architecture for Breakthrough Starshot.

A subsequent study, Project Andromeda, has provided input to Breakthrough Starshot prior to its announcement in 2016.

[27][28][29][30] Venus astrobiology mission: Subsequent to the alleged discovery of phosphine in the Venusian atmosphere in 2020, i4is published a study on a dedicated astrobiology mission, based on a fleet of balloons to probe the Venusian atmosphere.