The injured tissue has a negative voltage compared to the central part of the body.
[3] The concept originates from the research of Carlo Matteucci and Emil du Bois-Reymond in the mid-19th century.
It has been found by Elmer J. Lund that establishing an artificial electrical field causing a current mimicking the current of injury could facilitate regeneration.
[5] This potential for a regeneration therapy was further studied by Robert O. Becker, who described this work in his book The Body Electric.
He found that the current of injury runs through the perineurium – through the myelin sheaths of the peripheral nerves.