The 3300 shares its powertrain and forward body components with the 4300 medium-duty truck (the replacement for the 4900).

Since 2009, the 3300 chassis has been bodied by IC Bus exclusively in the United States and Canada.

At the time of its introduction, the International 3300 was sold exclusively with Navistar-sourced diesel engines.

Produced primarily as a school bus and as its commercial-market derivatives, the BE was designed for operators transporting special-needs passengers.

As an alternative to van-based buses, the BE was designed with a flat-floor interior, maximizing the available space for wheelchair passengers.