The film was researched and presented by activist Mani Mitchell, New Zealand's first "out" intersex person.

[1][3] The film follows Mitchell on a tour, visiting intersex people in America, Ireland, Germany, South Africa and Australia.

Interviews with sex researchers are also included, as well as some history of the treatment of intersex conditions.

[1] The cast of Intersexion includes intersex activists from around the world, including Mani Mitchell, Bo Laurent, also known as Cheryl Chase, Caitlin Petrakis Childs, Gavan Coleman, Jim Costich, Tiger Devore, Sally Gross, Esther Morris Leidolf, Stephanie Long, Pidgeon Pagonis (then known as Jen), Michel Reiter, David Cameron Strachan, Anne Tamar-Mattis, Suegee Tamar-Mattis, Peter Trinkl, Hida Viloria and Gina Wilson.

Graham Adams, writing for New Zealand magazine Metro describes how, "while the frankness of his subjects can be arresting, Lahood's interest in them is never prurient, or patronising.