[5] The route continues northeast toward Fancy Gap and passes under the Blue Ridge Parkway, with access to it and the town provided by a diamond interchange with SR 775, which has a connection to US 52.

The route begins a wrong-way concurrency with I-81 and US 11, with the northbound direction cosigned with southbound I-81 and US 11.

The Interstate was extended from Bland to the West Virginia border in 1974–1975; this extension included the East River Mountain Tunnel.

The Interstate existed in two separate segments until 1987, when the I-81/I-77 overlap between Wytheville and Fort Chiswell was built.

I-77 in Fancy Gap has been the site of many fatal accidents, often due to fog and wind in the mountains.