Iowa 160, known locally as Oralabor Road, passes to the south of the main campus of Des Moines Area Community College (DMACC).

It passes beneath a pedestrian bridge built in 2022 as an extension of the High Trestle Trail.

[3][4] Just 0.3 miles (480 m) from its eastern end, it intersects Delaware Avenue, a north–south street which diverts retail traffic exiting from I-35 just to the east.

It was built by the Iowa State Highway Commission, but the entire costs were borne by the federal government as part of the war effort.

In 1961, work began on reconstructing the intersection with Iowa 60 into a "one-level interchange", which provided each traffic movement a dedicated lane.