Ireneo Affò (born Davide, 10 December 1741 – 14 May 1797)[1] was an Italian art historian, writer, numismatist and Franciscan friar.

He began to cultivate the study of learning, conducting extensive historical research of Italy and the surrounding area.

Ferdinand, Duke of Parma sent Affò to serve as a professor of philosophy at Guastalla in 1768,[2] where he oversaw the publication of two ancient codices, including Angelo Poliziano's Orpheus, and the newly discovered archive of the Holy Spirit in Reggio Emilia.

His major work in the literary field is still represented by the first five volumes of Memoirs of writers and scholars of Parma (1789 – 1797).

In 1785, he became director of the Palatine Library in that city and later became historiographer of the Journal of the Duchy and honorary Professor of History at the university.