[2] In 1935 she joined the Fox studio (as Iris Shunn),[3] as a member of its stock company, playing incidental roles without screen credit.

She was released after one year and joined Columbia Pictures, which changed her screen name to Iris Meredith and promoted her immediately to leading-lady status.

She also worked in Columbia short subjects, notably the serials The Spider's Web (1938), and Overland with Kit Carson (1939), and a two-reel comedy with Charley Chase, His Bridal Fright (1940).

In her late fifties, she was diagnosed with oral cancer that resulted in the surgical removal of part of her jaw and tongue, which disfigured her face and affected her speech.

She seldom appeared in public, but in 1975 she did accept an invitation to a convention of western and serial fans, where she wore a veil over her face and was treated as a special guest.