[1] In the late 18th century BC, Zitraddu, the governor of the city, rebelled against its overlord Yarim-Lim.
[2] After the fall of Aleppo, the capital of Yamhad, to the Hittite king Mursili I (c. 1590 BC), Irridu came under the control of Mittani.
During the reign of Šuppiluliuma I of Hatti (c. 1350 BC), under prince Piyassili,[3] occupied Irridu in their advance upon the Mittanian capital Washukanni and after the Hittites retreated, it became a regional center for Mittani until it was conquered by Adad-nirari I, king of Assyria.
The royal family of Mittani escaped to Irridu but the Assyrians found them and deported them to Assyria.
Irridu and many cities in its area were set on fire, destroyed, and sowed with salty plants.