Born in Sergipe, Isaías began his career at his hometown club, EC Propriá.
He also played for Lagartense and CS Sergipe before arriving in Portuguese football at FC Penafiel.
He also played for Leça, where he won the second division, and later for Boavista, being champion of the Portuguese Cup in 1996–1997.
In 1999 he arrived at Cruzeiro where he won the Recopa Sudamericana and the Copa Centro-Oeste.
[1][2] Isaías died after losing control of his car on BR-101, in the municipality of Capela, Alagoas, on 4 December 2007.