Isaac Hardenbergh House, also known as The Hardenbergh Manor, is a historic home located at Roxbury in Delaware County, New York, United States.

It was built about 1790 and consists of a 2-story, five-bay center-entrance stone structure with a smaller 1+1⁄2-story frame addition built about 1820.

Also on the property is a board and batten horse and carriage barn, the ruins of a large dairy barn, and gateposts partially constructed of millstones.

[2] It was listed on the National Register of Historic Places in 1994.

This article about a historic property or district in Delaware County, New York, that is listed on the National Register of Historic Places, is a stub.