Isaac and Miria are a pair of idiotic and eccentric lovers who dress up in costumes and commit strange robberies in Prohibition-era United States.
[3] Within the series, set during the Prohibition-era of the United States, Isaac and Miria "are a pair of idiotic lovers and thieves" who are portrayed as "always enthusiastic and optimistic".
[7] Miria exhibits a complete trust in Isaac and supports anything he says no matter how ridiculous it is and often goes as far to mimic his body language and his speech, although she often does not really know what she is saying.
[6] Isaac and Miria may have been born into wealthy families because they state that their parents' homes and the Genoard mansion have similar exteriors.
When attempting to buy several disguises, they briefly meet Camorristi Firo Prochainezo and Maiza Avaro[8] and befriend the homunculus Ennis, instilling her with confidence and hope.
The pair sneak into the Martillo's speakeasy, the Alveare, to scout the area, and while they are in the storage room, Isaac is nearly killed by a ceremonial gunshot from Firo's caporegime inauguration downstairs.
Firo, not realizing what it was, had stolen it earlier and distributed it at the celebration, bestowing immortality and eternal youth on all the guests, including Isaac and Miria.
[9] In the anime series, the bottle the pair stole is truly the immortality elixir and they inadvertently distribute it at the party as a gesture of thanks toward the Martillo.
[9] In the two Grand Punk Railroad novels, set during late 1931, the pair receive a letter from Ennis and decide to visit her in Manhattan.
[17] When Tim and the Larvae arrive at the mansion, they believe that the display of Dallas' immortality is a magic trick and the fights are dances.
After everyone departs the mansion, the duo decide to "steal" Ronnie Sukiart and Ennis, two people precious to Firo, in an attempt to make him apologize.
[6] Isaac is released later in the year and reunites with Miria in Chicago, as told in Conclusion Chapter Peter Pan In Chains.
[20] Isaac and Miria appear in the series' two drama CDs; they survive the Flying Pussyfoot incident in 1931 Local Chapter ・ Express Chapter The Grand Punk Railroad[21] and hope to meet true revolutionaries in a small Mexican village in Firo Prochainezo witnesses the 53rd death of Pietro Gonzalez.
anime series, voiced by Sam Riegel and Jennie Kwan in the English dub, during which they are in modern-day Ikebukuro, Tokyo and attend the first meeting of the Dollars, an anonymous online gang.
[25][26] Isaac and Miria have been named one of two of 2009's "Duo of the Year" by Theron Martin of Anime News Network (ANN).
He believed that they are "endlessly entertaining" because of their "kooky natures, dimwittedness, and talents for both disrupting the intended flow of any situation and succeeding despite themselves".
"[28] Although Surat and Tool were not opposed to the English dubbing, they felt that Isaac's accent sounded weird and "might get on someone's nerves.
[32] Chris Beveridge from Mania Entertainment described the two as "very off center in a colorful and fun way" and believed they stood out from the large cast because they were "far more outgoing.
"[34][35] DVD Talk's Todd Douglass felt that Isaac and Miria are "the uplifting and energetic component of [the] show," feeling that it is entertaining to see how they influenced the events.
He described them to be filled with "a maniac energy, often brought to a screeching halt by melodramatic breakdowns over trivial occurrences or bold assumptions."
He comments that as the plot progresses, the pair "become a bright spot as storylines take dark turns and serve as a reminder of the goodness that makes up the vast majority of the world.